Would you like to participate in HG Progress? We have research opportunities for currently pregnant moms with and without HG. Please participate.
HELP Score Validation
We are doing an important survey to validate the HELP Score (HyperEmesis Level Prediction Score) which tells us how severe HG is today.
We need women to fill out this survey; before and after they have a change in treatment. Start by filling it out the day before you get medical care like IV fluids or new medication; then fill it out again about 12-24 hours later. If you’re in the hospital, please try to fill it out once each day. The first survey is a little longer than the follow-up 24 hours later because we have to collect your pregnancy history and other standard research information, so feel free to start anytime. Most importantly, we need to see how your score changes with treatment. Please invite also women without HG to be our control group. Thanks!!
Nutrition Assessment Study
We know that women with HG often suffer more because of vitamin deficiencies. This nutrition assessment study will help us prove that.
If you are pregnant, please fill out the research survey
online. You can do it on your phone or your friend/family member can ask you the questions and fill it out for you. Please fill it out on more than one day, especially after you receive IV nutrition or vitamins. It will take about 10 minutes. You can save it part way if needed and finish later.
Note: A family member can enter your data for you.
If you have feedback, email Kimber@HelpHER.org.
Thank you for your time and for being part of HG progress!
This year, we are celebrating HG Awareness all month long because the HER/UCLA/USC team has identified the first cause of HG! That is truly groundbreaking and only happened due to your donations and participation! Let’s spread the message far and wide that no longer can others erroneously claim HG is a psychological disorder! See all the activities on our FB Events page. Here is a summary:
- Thunderclap – shout the message simultaneously!
- Facebook Live on May 15
- Meetup with another HG family
- Donate to get more answers
- Use our Facebook frames
- Share our posts on social media
What is the HG breakthrough we co-published in Nature Communications?
This study provides scientific evidence linking 2 genes, GDF15 and IGFBP7, to HG. These genes provide the instructions to build the proteins GDF15 and IGFBP7 in the human placenta during pregnancy. The proteins are known to be important in the development of the placenta and in controlling appetite. We have done additional work presented at the ICHG (vimeo.com/260389622) showing that not only are these genes linked to HG, but also, the proteins are abnormally high in the blood from patients hospitalized with HG.
HER Foundation helps UCLA, USC and 23&Me link debilitating pregnancy illness to two genes
FINALLY A BREAKTHROUGH FOR women suffering from the severe pregnancy illness, hyperemesis gravidarum (HG). Many people remember Princess Kate Middleton being hospitalized during her first pregnancy due to the severity of the disorder. However, other women affected by the pregnancy illness have limited family size, quit their jobs or sadly felt so desperate due to the debilitating illness that they terminated wanted pregnancies. Many HG women describe the illness as something no one can truly understand unless they have endured it themselves. Instead of the joy every pregnancy should bring, HG women spend most of the 9 months suffering in silence unable to eat or simply keep water down.
The HER Foundation, researchers at UCLA and USC, and 23andMe, Inc. conducted the first genome-wide analysis of Hyperemesis Gravidarum (HG) and identified two genes associated with HG, which was published this week in Nature Communications. (https://www.nature.com/articles/s41467-018-03258-0). Continue reading
Do you believe in our goal of improving HG management so moms & babies have a healthy future? DATA leads to PROGRESS!! So we need YOU – try our free iPhone app TODAY! Why is this app SO CRITICAL?? Imagine this… [See instructional demo!]
- Imagine slow research studies replaced by real-time data from the app being used to develop effective treatment protocols!!
- Imagine being able to easily communicate to your health professionals exactly what medications you took and how sick you truly are!
- Imagine seeing how much (or little) you’ve eaten and if your treatments are working after just 5 minutes each day using the app.
- Imagine getting alerts when your weight drops or you are getting dehydrated and need to go to the ER before your condition is serious!
- Imagine being reminded to take your meds and change your IV dressing if needed.
Imagine no more! This app will do all that and more! If we get enough participation and feedback, we can finalize this HG Care App project and moms enduring HG will finally have hope for real progress very soon! Progress means OUR CHILDREN won’t suffer as we have!
This app will NOT be completed without YOUR participation! This is a ONCE in a lifetime opportunity for the HG community thanks to #HERFoundation and #UCLA! Please join today!If you are not pregnant or using an iPhone, share this post and educate others on the CRITICAL need for this app. It’s NOW OR NEVER!!
The International Colloquium on HG in London (Oct 5-6) was a great success! Two presentations (1, 2) explained how ketones should not be required to be diagnosed with HG or given treatment. Some women are denied IV fluids if they do not have ketones.
What are ketones? They are produced when the body is starving and uses fat versus carbohydrates as fuel.
Ketones do not always correlate with weight loss or symptoms severity. They do predict a longer duration of hospitalization.
A study published by UCLA and supported, in part, by the Hyperemesis Education and Research Foundation found no evidence linking Zofran to birth defects.
“What was really significant to me was that women with extreme morning sickness who took Zofran reported fewer miscarriages and terminations and experienced higher live birth rates,” Fejzo said. “Taking this medication helped them get through their pregnancies and gave them their desired outcome, a live birth.”
Marlena Fejzo, PhD
Source: UCLA Health
Read the full study or HER Foundation collaborative research. Continue reading
Read our new (PDF) brochure you can print and share. Find out how to optimize your medications and learn how to use them to manage HG most effectively.
The HER Foundation is bringing the voices of HG women to a research conference at the University of Pittsburgh in early October. The Biology and Control of Nausea and Vomiting 2013 is targeted to both basic researchers and clinical investigators working in the field of nausea and vomiting. The conference will be useful for clinicians needing up-to-date information about treatments for nausea and vomiting, such as in patients suffering from hyperemesis gravidarum (HG).
One of the reasons the HER Foundation was created was to fund much needed research on HG. With the help of UCLA’s David Geffen School of Medicine we have funded over $46,000 in research grants. Thanks to all of the HG moms who have participated in our research! Because of you, UCLA has been able to identify medications (antihistamines) and other factors (gestational hypertension, early symptoms) linked to preterm birth and low birthweight babies in hyperemesis pregnancies. See Table 5 for the list of over 35 medications/treatments used compared to pregnancy outcomes and effectiveness. Share this research with your medical providers so you can make informed decisions together on how to treat your HG.
Download the Full Study Here.