Current Research Opportunities
HER Foundation and University of California at Los Angeles Collaboration
Current Study: Genetics of Hyperemesis Gravidarum (HG)
HG Researchers need your help! This study is designed to identify individuals affected with HG, to study epidemiologic factors via an online survey, to collect DNA samples from saliva through the mail at no cost or travel for you, and to search for genes and risk factors that may be potentially associated with this condition. To be eligible, you must have suffered from HG and had treatment for your HG that includes i.v. hydration, TPN or other form of non-oral feeding (ie nasogastric feeding), OR both, and are able to recruit a friend with at least 2 pregnancies who has NOT suffered from HG to serve as a control. If you live in the United States and are interested, please contact Marlena Schoenberg Fejzo, PhD at or 310-210-0802. Download the UCLA Consent Form (PDF) for more details about the study.
Once you have a study ID number, you can begin your survey at this link: http://www.helpher.org/HER-Research/2007-Genetics/
Identification of genes and risk factors that contribute to HG will lead to a better understanding of the causes of severe nausea and vomiting of pregnancy, and should be a first step toward the development of more effective treatments or a cure for this devastating disease. To learn more about why Marlena is devoted to finding the cause of HG and information about participating in the study watch Marlena's youtube.com video here.
- HG SEVERITY INDEX - Support our efforts to validate a NEW clinical tool for clinicians and mothers to evaluate the severity of their HG symptoms. While most scoring tools just assess the frequency of nausea and vomiting, this tool looks at the many factors that make up HG including how much you can eat/drink and how hard it is for you to function. If you are currently pregnant with HG, please click this link or scan the QR code to the right with your mobile device and fill out our brief survey. You can return and fill it out as your symptoms change. If you are participating in the above study, note your ID number for this survey if possible. A PDF printable form is also available. The final version will be available soon as it is being validated.
- CHILD FOLLOW UP FORM VIA GOOGLE DOCS
- Direct Link To Google Form (smartphone friendly)
Other HER Foundation Surveys and Polls
- 2004-2005 HG Survey: Complications & genetic issues related to HG, a comparison of pregnancies with and without HG
- 2002-2005 HG Survey: Treatment of HG & Termination
- "Impact on Daily Life" Poll
- "Postpartum Emotional Health" Poll
- "Emotional Trauma after HG" Poll
- "Duration of HG" Poll
- "Unwillingness of Insurers to Pay for HG Treatment" Poll
Although hyperemesis gravidarum (HG) affects thousands of women annually,
few research studies are published annually in comparison to other disorders.
We collaborate with experts on research related to HG, as well as conduct
semi-annual, online surveys and polls to further our understanding of
HG and its treatment. Our Internet research allows us to capture data
from around the globe on much larger numbers of participants. Most studies
done on HG have less than 200 participants, are not controlled or randomized,
and/or may not have enough evidence to support conclusions. Our studies
often have over 1000 participants with HG, and we are able work with international
experts on HG.
In short, too often HG studies do not meet current research standards. Thus, we aim to conduct and fund research that accurately defines the incidence, outcomes and proactive management of HG to help women get the care they and their unborn child need to survive. We accept donations to sponsor research grants.
Other HG Research Opportunities
Motherisk conducts studies to investigate the safety and efficacy of medications during pregnancy. If you are currently pregnant and would like to participate in their studies, see their website or call their toll free NVP Helpline at 1-800-436-8477 to enroll in a study. Participation usually involves brief phone interviews, that are strictly confidential. Review Motherisk's Current Studies
Governmental Studies (US)
Pregnancy Registry (FDA/Office of Women's Health) If you are pregnant and currently taking medicine — or have been exposed to a medicine during your pregnancy — you may be able to participate and help in the collection of needed information. This web site provides a list of pregnancy registries that are seeking participants.
ClinicalTrials.gov is a service of the National Institutes of Health Developed by the National Library of Medicine. You can search for research studies in which to participate as well as investigate the findings of medical research.
Updated on: Sep. 06, 2016